Sustainable Development Goal (SDG3) is dedicated to ensuring health lives and promoting well-being for all. How well is the Americas Region moving towards this goal? In chapter 4 of Health in the Americas we look at this progress through three lenses: how well countries are reducing preventable deaths of 1) mothers during childbirth, 2) newborns in the first month of life, and 3) adults from preventable chronic, noncommunicable diseases.